Phytochemical screening, antibacterial, antioxidant, and anticancer activity of Coffee parasite acetone extract (Loranthus ferrugineus Roxb)

Juwitaningsih, Tita and Roza, Destria and Silaban, Saronom and Hermawati, Elvira and Windayani, Neneng (2022) Phytochemical screening, antibacterial, antioxidant, and anticancer activity of Coffee parasite acetone extract (Loranthus ferrugineus Roxb). Pharmacia, 69 (04). pp. 1041-1046. ISSN 0428-0296

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Abstract

This study aimed to perform a phytochemical screening and test the antibacterial, antioxidant, and anticancer activities of acetone extracts of the Coffee parasite (Loranthus ferrugineus Roxb). A phytochemical screen was performed using specific reagents. Antimicrobial testing was performed using the paper disc diffusion method. The antioxidant activity test used the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Anticancer activity test against HeLa and A549 cells based on the 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay method. Acetone extract L. ferrugineus Roxb contains alkaloids, flavonoids, triterpenoids, and tannins compounds. The acetone extract of L. ferrugineus Roxb showed activity against all the bacteria tested, with the inhibition zone diameter ranging from 6.2 mm - 11.1 mm. Acetone extract of L. Ferrugineus Roxb had a very strong antioxidant activity with a value of IC50 = 48.7122 μg/mL. The anticancer activity test showed cytotoxic activity against HeLa cells with a value of IC50 = 47.62 μg/mL and for A549 cells with a value of IC50 = 192.83 μg/mL.

Item Type: Article
Keywords: Antibacterial; Antioxidant; Anticancer; Loranthus ferrugineus Roxb; Phytochemical screening
Subjects: Q Science > QD Chemistry > QD241 Organic chemistry
Q Science > QD Chemistry > QD450 Physical and theoretical chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Kimia
Depositing User: Mrs Harly Christy Siagian
Date Deposited: 04 Apr 2023 04:38
Last Modified: 20 Jun 2023 02:28
URI: https://digilib.unimed.ac.id/id/eprint/51627

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