Brahmana, Eti Meirina (2016) SINTESIS SENYAWA KALKON (E)-1-(4-KLOROFENIL)-3-ISOPROPILFENIL)PROP-2-EN 1-ON DAN UJI TOKSISITASNYA. In: Seminar Nasional Kimia dan Pendidikan Kimia 2016, 30-31 May 2016, Medan.
Preview
Fulltext.pdf - Published Version
Download (724kB) | Preview
Abstract
Halogen substituted analogoues compounds chalcone, (E)-1-(4-klorofenil)-3-(4-isopropilfenil) prop-2-en-1-on, was synthesized from 4-isopropilbenzaldehyde as aldehydes with 4-chloroacetophenone as ketones by using aldol condensation reaction. The compound resulted rendement with value of 64,90% and characterized by using UV, IR, MS, and 1HNMR. Toxicity tests using Brine Shrimp Lethality Test (BSLT) showed that those compounds have a potency as anticancer agent with LC50 value 3,98 μg/mL.
Item Type: | Conference or Workshop Item (Paper) |
---|---|
Keywords: | Chalcone; Halogen; Toxicity tests |
Subjects: | Q Science > QD Chemistry > QD146 Inorganic chemistry Q Science > QD Chemistry > QD450 Physical and theoretical chemistry |
Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam |
Depositing User: | Mrs Harly Christy Siagian |
Date Deposited: | 20 Mar 2017 05:05 |
Last Modified: | 21 Mar 2017 03:51 |
URI: | https://digilib.unimed.ac.id/id/eprint/23730 |