SINTESIS SENYAWA KALKON (E)-1-(4-KLOROFENIL)-3-ISOPROPILFENIL)PROP-2-EN 1-ON DAN UJI TOKSISITASNYA

Brahmana, Eti Meirina (2016) SINTESIS SENYAWA KALKON (E)-1-(4-KLOROFENIL)-3-ISOPROPILFENIL)PROP-2-EN 1-ON DAN UJI TOKSISITASNYA. In: Seminar Nasional Kimia dan Pendidikan Kimia 2016, 30-31 May 2016, Medan.

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Abstract

Halogen substituted analogoues compounds chalcone, (E)-1-(4-klorofenil)-3-(4-isopropilfenil) prop-2-en-1-on, was synthesized from 4-isopropilbenzaldehyde as aldehydes with 4-chloroacetophenone as ketones by using aldol condensation reaction. The compound resulted rendement with value of 64,90% and characterized by using UV, IR, MS, and 1HNMR. Toxicity tests using Brine Shrimp Lethality Test (BSLT) showed that those compounds have a potency as anticancer agent with LC50 value 3,98 μg/mL.

Item Type: Conference or Workshop Item (Paper)
Keywords: Chalcone; Halogen; Toxicity tests
Subjects: Q Science > QD Chemistry > QD146 Inorganic chemistry
Q Science > QD Chemistry > QD450 Physical and theoretical chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam
Depositing User: Mrs Harly Christy Siagian
Date Deposited: 20 Mar 2017 05:05
Last Modified: 21 Mar 2017 03:51
URI: https://digilib.unimed.ac.id/id/eprint/23730

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