Antibacterial activity of mandailing traditional plant leaves ethanol extract of Mikania micrantha

This study aims to determine the antibacterial activity of the ethanol extract of Mikania micrantha leaves. The test bacteria used in this study were Escherichia coli, Salmonella typhi, Staphylococcus aureus, Enterobacter aerogenes, Staphylococcus epidermis obtained from a collection of bacterial cultures of the Medan State University microbiology laboratory. The leaves used in the study were Mikania micrantha leaves obtained from Mandailing Natal District, North Sumatra. ethanol extraction method using soxhlet method. The results showed that the best concentration in inhibiting bacterial growth was at a concentration of 30 mg/ml. The largest inhibitory zone formed is Staphylococcus aureus bacteria at 9.33 mm. the conclusion obtained in the study is that the greater the concentration level of the Mikania micrantha leaf ethanol extract, the greater the inhibition zone is formed.