LIVER FUNCTION TEST ELEVATION IN MODERATE INTENSITY PHYSICAL EXERCISE

Liver enzymes can be used as a sign of liver injury include Serum Alanine Amino Transferase (ALT) also called Serum Glutamic Pyruvic Transaminase (SGPT) and Serum Amino Transferase Aspartate (AST) also called Serum Glutamic Oxaloacetic Transaminase (SGOT). Elevation of liver transaminase is generally caused by liver injury due to liver diseases and also may be elevated by extra hepatic process such as physical exercise. However, there is no consensus on what type of exercise can cause liver function test elevation. Moderate intensity of physical activity was being carried out by running on a treadmill with an intensity of 70% 80% of the maximum heart rate for one hour. Then, blood sample was taken to measure SGOT and SGPT. Data obtained were statistically analyzed using paired t-test with a significance level of below 0.05 (p<0.05) and 95% confidence level (α=0.05). Serum SGOT was increased 1.8 times, mean 39.54 u/L, p<0.001. Serum SGPT was increased 1.7 times, mean 49.4 u/L, p=0.002. Moderate intensity of physical activity could increase significantly liver function tests. However, more research is needed to compare the liver function test elevation among mild, moderate, higher intensity physical exercise.