Evaluation of North Sumatera Cardamom seed (Amomum compactum) Extract as Antibacterial and Anticancer

Juwitaningsih, Tita and Jahro, Iis Siti and Sari, Sri Adelila (2020) Evaluation of North Sumatera Cardamom seed (Amomum compactum) Extract as Antibacterial and Anticancer. In: UNSPECIFIED.

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Abstract

Cardamom seeds (Amomum compactum) or Kapulaga have been used as a flavoring spice in cooking. Besides, they are also useful in traditional medicine for oral health and
gizzard, treating coughs and colds, maintaining kidney and urinary health, pain medication, preventing infections, as well as smoothing digestion. This study was aimed to evaluate the acetone extract of North Sumatera A. compactum as antibacterial and anticancer. The antibacterial activity test was carried out by the paper disc diffusion method. It was then followed by determination of minimum inhibitory concentration (MIC) and minimum kill concentration (MBC) against S. aureus ATCC 25923, S. mutans ATCV 35668 and E. faecalis
ATCC 49619. The cytotoxic test was performed against MCF-7 cells. It has been found that acetone extract of A. compactum showed the best activity against S.aureus ATCC 25923 with a diameter of inhibition zone was of 8.3mm with MIC and MBC values of 625μg/mL. Acetone extract of A. compactum has anticancer breast activity with IC50 value was found to be 44.7828 μg/mL.

Item Type: Conference or Workshop Item (UNSPECIFIED)
Keywords: North Sumatera Cardamom Seed (Amomum campactum); acetone extract; antibacterial; and breast anticancer (MCF-7)
Subjects: Q Science > QD Chemistry
Q Science > QD Chemistry > QD71 Analytical chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Kimia
Depositing User: Mrs Elsya Fitri Utami
Date Deposited: 30 Jun 2020 07:33
Last Modified: 27 Jun 2023 06:55
URI: https://digilib.unimed.ac.id/id/eprint/39703

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