ANTIOXIDANT, TOXICITY AND ANTIBACTERIAL OF OMPU-OMPU (Crinum asiaticum-L) ETHANOL EXTRACT

The Crinum plant varieties found, called “Ompu-ompu”, identified as a type of Crinum asiaticum-L which used as a drug. The antioxidant, toxicity and antibacterial of the Crinum leaves and bulbs extracted with ethanol and treated by DPPH (2-2 diphenyl 1-1-picrylhydrazyl) method, Brine Shrimp Lethality Test (BSLT) method, and diffusion method respectively. It was found that both the leaves and bulbs have an antioxidant site with 54.21 ppm and 33.79 ppm respectively through IC50 test 25.8 ppm which used vit.C as a control. Furthermore, it was found that their toxicity measured by LD50 is 243.331 and 507.838 respectively. In addition, the antibacterial test showed that the widest inhibition of the leaves and bulbs are 15.7 mm and 12.4 mm against Escherichia coli respectively and 12.3 mm and 11.5 mm against Staphylococcus aureus. Phytochemical screening indicated the presence of alkaloids, flavonoid, saponins and tannins.