INHIBITION OF -GLUCOSIDASE FOR WATER EXTRACT OF RARU (Vatica pauciflora Blume)

This study is aimed to determine antidiabetic activity based on -glucosidase inhibition to some water extracts of the parts of Raru (Vatica pauciflora Blume). Results showed that -glucosidase inhibition activity of bark extract (IC50 13.53 ppm) was higher than those of other extracts (leaves and roots exhibited IC50 16.96 ppm and 41.91 ppm respectively). While IC50 for acarbose compound (positive control) is 10.51 ppm. The chemical compound groups observed in the water extract of barks are tannin gallate, tannin catecuate, saponine and triterpenoids.