BURN WOUND HEALING ACTIVITY OF ETHANOLIC EXTRACT OF ACALYPHA INDICA IN OINMENT FORMULATED AGAINST RABBITS (OCYCTAGUS CANICULUS)

Fitri, Khairani and Khairani, Tetty Noverita and Sinaga, Fajar Apollo and Taluhoni, Amenia Gracia (2020) BURN WOUND HEALING ACTIVITY OF ETHANOLIC EXTRACT OF ACALYPHA INDICA IN OINMENT FORMULATED AGAINST RABBITS (OCYCTAGUS CANICULUS). Asian Journal of Pharmaceutical Research and Development, 08 (03). pp. 18-20. ISSN 2320-4850

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Abstract

Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated.

Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing.

Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base.

Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase.

Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.

Item Type: Article
Keywords: Acalypha indica L.; Ethanolic extract; Oinment; Wound healing
Subjects: R Medicine > RA Public aspects of medicine > RA773 Personal health and hygiene
R Medicine > RS Pharmacy and materia medica > RS153 Materia medica > RS160 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Divisions: Fakultas Ilmu Keolahragaan
Depositing User: Mrs Harly Christy Siagian
Date Deposited: 10 Nov 2022 07:02
Last Modified: 10 Nov 2022 07:02
URI: https://digilib.unimed.ac.id/id/eprint/49083

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