Sinulingga, Karya and Sirait, Makmur and Siregar, Nurdin and Doloksaribu, Maryati Evivani (2021) INVESTIGATION OF ANTIBACTERIAL ACTIVITY AND CELL VIABILITY OF Ag/Mg AND Ag/Zn Co-DOPED HYDROXYAPATITE DERIVED FROM NATURAL LIMESTONE. ACS Omega, 06 (49). pp. 34185-34191. ISSN 2470-1343
Text
Fulltext.pdf - Published Version Download (0B) |
|
Text
Reviewer.pdf - Published Version Download (0B) |
|
Text
Turnitin.pdf - Published Version Download (0B) |
|
Text
Reviewer 2.pdf - Published Version Download (0B) |
|
Text
LOA Omega.pdf - Published Version Download (0B) |
|
Text
Reviewer 3.pdf - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_lightbox)
lightbox.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_preview)
preview.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_medium)
medium.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_small)
small.jpg - Published Version Download (0B) |
|
Other (Generate index codes conversion from text to indexcodes)
indexcodes.txt - Published Version Download (0B) |
|
Other (Generate index codes conversion from text to indexcodes)
indexcodes.txt - Published Version Download (0B) |
|
Other (Generate index codes conversion from text to indexcodes)
indexcodes.txt - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_lightbox)
lightbox.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_preview)
preview.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_medium)
medium.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_small)
small.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_lightbox)
lightbox.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_preview)
preview.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_medium)
medium.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_small)
small.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_lightbox)
lightbox.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_preview)
preview.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_medium)
medium.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_small)
small.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_lightbox)
lightbox.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_preview)
preview.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_medium)
medium.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_small)
small.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_lightbox)
lightbox.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_preview)
preview.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_medium)
medium.jpg - Published Version Download (0B) |
|
Other (Thumbnails conversion from text to thumbnail_small)
small.jpg - Published Version Download (0B) |
Abstract
Improving the antibacterial activity to avoid infections and keeping the biocompatibility at a safe level of HAp-based materials is highly important for biomedical applications. In this work, we investigate the antibacterial activity of 2.5Ag/2.5Mg co-doped HAp and 2.5Ag/2.5Zn co-doped HAp toward Escherichia coli bacteria. Moreover, their biocompatibility for osteoblastic cells (MC3T3-E1 cells) was also evaluated. The physical properties were characterized with necessary characterization tools such as X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Brunauer−Emmett−Teller. Both 2.5Ag/2.5Mg and 2.5Ag/2.5Zn co-doped HAp consist of hydroxyapatite (HAp) and beta calcium triphosphate (β-TCP) phases. The antibacterial test reveals that 2.5Ag/2.5Mg co-doped HAp or 2.5Ag/2.5Zn co-doped HAp has an outstanding antibacterial activity with a killing rate of 99 ± 1%. More importantly, the cell viability for osteoblast cells with 2.5Ag/2.5Mg and 2.5Ag/2.5Zn co-doped HAp promotes the proliferation much more effectively than 2.5Ag-doped HAp or 5Ag-doped HAp.
Item Type: | Article |
---|---|
Keywords: | Antibacterial; Cell viability; Hydroxyapatite; Natural limestone |
Subjects: | Q Science > QC Physics Q Science > QC Physics > QC120 Descriptive and Experimental mechanics |
Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam > Pendidikan Fisika |
Depositing User: | Mrs Harly Christy Siagian |
Date Deposited: | 10 Mar 2022 08:09 |
URI: | http://digilib.unimed.ac.id/id/eprint/45693 |
Actions (login required)
View Item |