HSP70 (HEAT SHOCK PROTEIN 70) EXPRESSION AND ANTIOXIDANT AS A PROTECTIVE AGAINST OXIDATIVE STRESS TRIGGERED BY SUB-MAXIMAL PHYSICAL ACTIVITY

Sub-maximal physical activity will interfere with the ROS and antioxidants balance, so oxidative stress occurs. Oxidative stress can induce increased expression of HSP70 in cells to produce a cytoprotective effect. Red dragon fruit in biological systems can neutralize free radicals, because it contains flavonoid compounds and polyphenols. There were 20 participants, male, athletes, non-smokers and 2 weeks before and during the study, no consumption of supplements and antioxidants. Participants were randomly divided into 2 teams. Team A had sub-maximal activity and no red dragon fruit given. Team B had activity sub-maximal and was given red dragon fruit juice. Study found that HSP70 expression was lower in the team B than in team A. There was significancy difference between team A and team B in expression of HSP70. We concluded that, HSP70 expression and antioxidants can be the protective function against oxidative stress triggered by sub-maximal physical activity.