ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF NONPOLAR TO POLAR SOLVENT EXTRACTS OF Sarang Banua (Clerodenrum fragrans Vent Willd) LEAVES

Nainggolan, Bajoka (2019) ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF NONPOLAR TO POLAR SOLVENT EXTRACTS OF Sarang Banua (Clerodenrum fragrans Vent Willd) LEAVES. RASĀYAN Journal of Chemistry [RJC], 12 (2). pp. 959-965. ISSN 0976-0083

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Abstract

Sarangbanua plant, known as Clerodendrumfragrans Vent Willd, is a division of the Verbanaceae family found in Simalungun district of Indonesia, which is traditionally used as medicinal plants. The antioxidant and antibacterial activities of the C. fragrans leave extract was prepared by dissolving it in non-polar to polar solvents and treated by DPPH (1,1- diphenyl-2-picrylhydrazin) and diffusion methods. The results showed that the ethanol (polar) extract of the C. fragrans leaves had the highest antioxidant activity than ethyl acetate (semi-polar) and n-hexane (non-polar) extracts, which had IC50 values of 22.37 ppm, 27.26 ppm, and 88.77 ppm respectively. Vitamin C as a positive controlled with the IC50 value of 20.18 ppm. Furthermore, the ethyl acetate (semi-polar) extract of the C. fragrans leaves had the greatest inhibition value on Gram-positive bacteria of S. aureus (90.0%)with inhibitory zones of 11.25 ± 0.2 mm, meanwhile the n-hexane (non-polar) extract had the greatest inhibition against Gram-negative bacteria of the E.coli(77.21%)with inhibitory zones of 10.5±0.3 mm

Item Type: Article
Contributors:
ContributionNameNIDN/NIDK
ReviewerSitumorang, Maniharnidn0004086011
ReviewerHutabarat, Weslynidn9990000089
Keywords: Clerodendrum fragrant Vent Willd; Antibacterial; Antioxidant; Polarity of solvent; Medicinal plant of Indonesian
Subjects: L Education > LB Theory and practice of education
L Education > LB Theory and practice of education > LB1603 Secondary Education. High schools
L Education > LB Theory and practice of education > LB2300 Higher Education > LB2361 Curriculum
Q Science > QD Chemistry
Q Science > QD Chemistry > QD415 Biochemistry
Q Science > QD Chemistry > QD71 Analytical chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam
Depositing User: Mrs Catur Dedek Khadijah
Date Deposited: 23 Dec 2020 09:46
URI: http://digilib.unimed.ac.id/id/eprint/40990

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