SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI TUMBUHAN SIDAGURI (SIDA RHOMBIFOLIA L.) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS, ENTEROCOCCUS FAECALIS DAN STREPTOCOCCUS MUTANS

CHAIRUNNISA, SITI (2018) SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI TUMBUHAN SIDAGURI (SIDA RHOMBIFOLIA L.) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS, ENTEROCOCCUS FAECALIS DAN STREPTOCOCCUS MUTANS. Undergraduate thesis, UNIMED.

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Abstract

Penyakit gigi dan mulut dapat disebabkan oleh bakteri Staphylococcus aureus, Enterococcus faecalis dan Streptococcus mutans. Penelitian ini bertujuan untuk mengetahui potensi ekstrak tumbuhan sidaguri (Sida rhombifolia L.) terhadap bakteri Staphylococcus aureus, Enterococcus faecalis dan Streptococcus mutans. Metode yang dilakukan pada penentuan zona hambat adalah metode difusi cakram kertas dan untuk penentuan MIC menggunakan mikrodilusi. Hasil uji fitokimia menunjukkan bahwa tumbuhan sidaguri mengandung alkaloid, flavonoid, tanin dan saponin. Berdasarkan uji aktivitas antibakteri yang dilakukan maka ekstrak tumbuhan sidaguri dapat digunakan sebagai antibakteri terhadap bakteri S.aureus, E.faecalis dan S.mutans dengan zona hambat masing-masing 7,9 mm; 6,8 mm; dan 10,3 mm. Adapun nilai MIC dan MBC untuk S.aureus adalah 625 (µg/mL) dan 625 (µg/mL) yang berarti ekstrak tidak hanya dapat menghambat tetapi juga dapat membunuh bakteri. Nilai MIC dan MBC untuk E.faecalis 625 (µg/mL) dan >5000 (µg/mL) yang berarti ekstrak hanya bersifat menghambat (bakteriostatik) dan nilai MIC dan MBC untuk S.mutans 1250 (µg/mL) dan 5000 (µg/mL) yang berarti ekstrak bersifat membunuh (bakterisidal).

Item Type: Thesis (Undergraduate)
Contributors:
ContributionNameNIDN/NIDK
Thesis advisorJUWITANINGSIH, TITANIDN196503041990032003
Call Number: SK-2018 KIM 143
Keywords: Sidaguri (Sida rhombifolia L.), Fitokimia, Antibakteri, Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans
Subjects: Q Science > QD Chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Kimia
Depositing User: Mr Renaldi Syafaruddin Akbar
Date Deposited: 09 Apr 2019 10:11
URI: http://digilib.unimed.ac.id/id/eprint/34278

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