, FITRIA (2018) PENGARUH EKSTRAK ETANOL DAUN PIRDOT (SAURAUIA VULCANI, KORTH.) TERHADAP KADAR GLUKOSA DARAH DAN HISTOPATOLOGI PULAU LANGERHANS PANKREAS TIKUS (RATTUS NORVEGICUS) DIABETES. Undergraduate thesis, UNIMED.
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Abstract
Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian ektrak etanol daun pirdot (Saurauia vulcani, Korth.) (EES) terhadap berat badan, kadar glukosa darah dan gambaran histopatologi pulau langerhans tikus (Rattus novergicus) diabetes dengan induksi aloksan. Jenis penelitian ini merupakanrancangan acak lengkap dengan lama perlakuan 28 hari. 25 ekor tikus jantan dibagi kedalam 5 kelompok perlakuan yaitu kontrol negatif, kontrol positif (aloksan 30 mg/ekor), aloksan 30 mg/ekor + EES 16,5 ekor, aloksan 30 mg/ekor + EES 33 mg/ekor, dan aloksan 30 mg/ekor + EES 66 mg/ekor. Hasil analisis data menunjukkan bahwa rata-rata berat badan pada kelompok dosis 16,5 mg/ekor dan 33 mg/ekor berbeda signifikan dengan kelompok kontrol kontrol positif. Sedangkan pada dosis 66 mg/ekor tidak berbeda signifikan dengan kelompok kontrol positif. Sedangkan rata-rata kadar glukosa darah terjadi penurunan yang jauh lebih besar pada dosis EES 16,5 mg/ekor. Pada pengamatan histopatologi pada kelompok perlakuan dengan pemberian EES terdapat perbaikan ditandai dengan berkurangnya sel-sel yang mengalami cloudy swelling.
Item Type: | Thesis (Undergraduate) | ||||||
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Call Number: | SK-2018 BIO 236 | ||||||
Keywords: | diabetes, aloksan, ekstrak etanol Saurauia vulcani, Korth. kadar glukosa darah, histopatologi pulau langerhans | ||||||
Subjects: | L Education > LB Theory and practice of education Q Science > QH Natural history > QH301 Biology |
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Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam > Biologi | ||||||
Depositing User: | Mr Renaldi Syafaruddin Akbar | ||||||
Date Deposited: | 21 Feb 2019 15:02 | ||||||
URI: | http://digilib.unimed.ac.id/id/eprint/32215 |
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