AKTIVITAS ANTIBAKTERI EKSTRAK BUAH RANTI HITAM (SOLANUM BLUMEI NEES EX BLUME) TERHADAP STAPHYLOCOCCUS AUREUS

Sirait, Yeni Yosevine (2014) AKTIVITAS ANTIBAKTERI EKSTRAK BUAH RANTI HITAM (SOLANUM BLUMEI NEES EX BLUME) TERHADAP STAPHYLOCOCCUS AUREUS. Undergraduate thesis, UNIMED.

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Abstract

Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri dari ekstrak buah ranti hitam (Solanum blumei Nees ex Blume) terhadap bakteri Staphylococcus aureus. Metode uji aktivitas antibakteri dilakukan dengan metode sumur difusi. Sampel yang digunakan adalah buah ranti hitam (Solanum blumei Nees ex Blume) yang berasal dari daerah Kuta Nangka, Kec. Tanah Pinem, Kab. Dairi. Ekstrak sampel yang diuji adalah ekstrak n-heksan, ekstrak etil asetat dan ekstrak etanol dengan konsentrasi masing-masing ekstrak adalah 0 ; 2,5 dan 5,0%. Sebagai kontrol positif digunakan kloramfenikol dan control negatif adalah pelarut ekstrak. Aktivitas antibakteri diukur dari luas diameter zona bening disekitar lubang. Hasil penelitian menunjukkan aktivitas antibakteri (diameter zona hambat) ekstrak buah ranti hitam (Solanum blumei Nees ex Blume) yaitu Ekstrak n-Heksan 0; 2,5; dan 5,0% adalah 0; 7,5; 8,5 mm. Ekstrak etil asetat berturut-turut pada konsentrasi 0; 2,5; dan 5% adalah 0; 11; 12,5 mm. Ekstrak etanol 0; 2,5; dan 5,0% adalah 0; 8,0 ; 8,2 mm. Kloramfenikol (kontrol positif) sebesar 13,5 mm. Potensi daya hambat ekstrak buah ranti hitam (Solanum blumei Nees ex Blume) terhadap Staphylococcus aureus dari yang terbesar secara berurutan adalah ekstrak etil asetat 5,0% (92,5%), ekstrak etil asetat 2,5% (81,4%), ekstrak n-Heksan 5,0% (62,9%), ekstrak etanol 5,0% (60,7%), ekstrak etanol 2,5% (59,2%) dan ekstrak n-Heksan 2,5% (55,5%). Fraksi ekstrak buah ranti hitam (Solanum blumei Nees ex Blume) yang memiliki aktivitas antibakteri yang terbesar terhadap Staphylococcus aureus secara berurutan adalah ekstrak etil asetat 5,0% (12,5 mm), ekstrak n-Heksan 5,0% (8,5 mm), dan ekstrak etanol 5,0% (8,2 mm).

Item Type: Thesis (Undergraduate)
Contributors:
ContributionNameNIDN/NIDK
Thesis advisorSimorangkir, Murniaty195905041984032001
Call Number: 547.76 Sir a
Keywords: antibakteri, staphylococcus aureus, solanum blumei nees ex blume dan buah.
Subjects: Q Science > QD Chemistry
Q Science > QR Microbiology > QR75 Bacteria
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Kimia
Depositing User: Mrs Desy Sry Yani
Date Deposited: 08 Apr 2016 08:34
URI: http://digilib.unimed.ac.id/id/eprint/11925

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